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Module VII – Respiratory tract infections Study Guide

Use Text book Pharmacotherapy (Principles &Practice) 5th edition, insect diagrams as needed

· Classification of medications, adverse effects, drug interactions, contraindications, monitoring, and patient counseling are always essential

· Have you reviewed the learning objectives on the introductory page for each topic and those found in the text?

· Bacterium are classified according to gram stain. What organisms make up the normal flora (fig 69-1) and what are the typical pathogenic organism the sites of infection discussed in this module

· Recognize terms such as resistance, susceptibility, pathogenicity, virulence, MIC, empirical therapy, definitive therapy, de-escalation

· LRTI

· Preventative strategies

· Risk factors

· Etiologies (common bugs) (table 71-1) … can’t treat an infection if you don’t know what causes it

· Treatment (
adults only, non-ICU
) (table 71-2) based on patient specific characteristics such as co-morbidities (eg diabetes, COPD), allergies (eg. PCN, macrolides, sulfa), drug interactions (quinolones + antacids/dairy, macrolides inhibit P450), CIs (tetracyclines in children), ADRs (clindamycin > c diff, quinolones > tendon rupture, QT prolongation, tetracyclines > photosensitivity), etc

· URTI (ARBS, AOM)

· Preventative strategies

· Risk factors (72-1, 72-3)

· Etiologies (common bugs)

· Treatment based on patient specific characteristics such as co-morbidities (eg diabetes, COPD), allergies (eg. PCN, macrolides, sulfa), drug interactions (quinolones + antacids/dairy, macrolides inhibit P450), CIs (tetracyclines in children), ADRs (clindamycin > c diff, quinolones > tendon rupture, QT prolongation, tetracyclines > photosensitivity), etc

· Figure 72-2, 72-3; table 72-2,72-4 (note comments in table)

· Common cold
– briefly
review table 72-6. The agents used are mostly OTC and are similar to those used in allergic rhinitis and will be re-visited again in a later module